Moderna (MRNA) United States $152.050B 46.97 Bristol Myers Squibb (BMY) United States $148.571B 9.89 Amgen (AMGN) United States $128.068B 13.87 CSL (CSLLY) Australia $103.760B 0.00 Gilead Sciences (GILD) United States $91.252B 8.82 BioNTech SE (BNTX) Germany $79.834B 17.23 Regeneron Pharmaceuticals (REGN) United States $72.024B 12.36 Illumina (ILMN) United States $67.065B 76.19 Biogen (BIIB) United States $50.509B 13.87 Genmab (GNMSF) Denmark $31.219B 78.03 Genmab (GMAB) Denmark $31.126B 76.43 Seagen (SGEN) United States $30.492B 51.41 BeiGene (BGNE) Cayman Islands $28.582B 0.00 Horizon Therapeutics Public (HZNP) Ireland $24.417B 23.15 Alnylam Pharmaceuticals (ALNY) United States $23.939B 0.00 Bio-Rad Laboratories (BIO.B) United States $22.711B 48.40 Bio-Techne Corp (TECH) United States $19.506B 87.72 Exact Sciences (EXAS) United States $17.948B 0.00 Novavax (NVAX) United States $17.767B 0.00 ARGENX SE-ADR (ARGX) Netherlands $17.028B 0.00 Incyte (INCY) United States $16.892B 40.05 Repligen (RGEN) United States $15.537B 118.40 BioMarin Pharmaceutical (BMRN) United States $15.440B 110.80 Zai Lab (ZLAB) China $13.787B 0.00 Guardant Health (GH) United States $12.892B 0.00 QIAGEN (QGEN) Netherlands $12.726B 21.55 CureVac (CVAC) Germany $12.305B 0.00 Intellia Therapeutics (NTLA) United States $11.797B 0.00 CRISPR Therapeutics AG (CRSP) Switzerland $9.521B 24.45 Mirati Therapeutics (MRTX) United States $8.762B 0.00 Biohaven Pharmaceutical Holding (BHVN) United States $8.583B 0.00 Ascendis Pharma (ASND) Denmark $8.437B 0.00 Acceleron Pharma (XLRN) United States $8.153B 0.00 Beam Therapeutics (BEAM) United States $7.360B 0.00 Fate Therapeutics (FATE) United States $6.972B 0.00 Vir Biotechnology (VIR) United States $6.732B 0.00 SWEDISH ORP BIO (BIOVF) Sweden $6.600B 23.66 Ultragenyx Pharmaceutical (RARE) United States $6.532B 0.00 Denali Therapeutics (DNLI) United States $6.471B 183.45 Sarepta Therapeutics (SRPT) United States $6.237B 0.00 Exelixis (EXEL) United States $6.039B 66.10 Halozyme Therapeutics (HALO) United States $5.977B 24.41 NeoGenomics (NEO) United States $5.971B 810.33 Apellis Pharmaceuticals (APLS) United States $5.729B 0.00 Twist Bioscience (TWST) United States $5.580B 0.00 Legend Biotech (LEGN) United States $5.541B 0.00 Blueprint Medicines (BPMC) United States $5.463B 15.42 I-Mab (IMAB) China $5.458B 0.00 Certara (CERT) United States $5.132B 0.00 Adaptive Biotechnologies (ADPT) United States $5.113B 0.00 Alkermes (ALKS) Ireland $5.043B 148.86 AbCellera Biologics (ABCL) $4.677B 0.00 Editas Medicine (EDIT) United States $4.341B 0.00 Arvinas (ARVN) United States $4.241B 0.00 Reata Pharmaceuticals (RETA) United States $3.876B 0.00 Galapagos (GLPG) Belgium $3.854B 0.00 SpringWorks Therapeutics (SWTX) United States $3.690B 0.00 Emergent Biosolutions (EBS) United States $3.387B 8.17 BAVARIAN NORDIC (BVNRY) Denmark $3.260B 0.00 Arena Pharmaceuticals (ARNA) United States $3.232B 0.00 Insmed (INSM) United States $3.232B 0.00 Kymera Therapeutics (KYMR) United States $3.172B 0.00 Amicus Therapeutics (FOLD) United States $3.036B 0.00 Prothena (PRTA) Ireland $2.965B 0.00 Heska (HSKA) United States $2.824B 541.43 ALX Oncology Holdings (ALXO) United States $2.824B 0.00 ACADIA Pharmaceuticals (ACAD) United States $2.813B 0.00 Myriad Genetics (MYGN) United States $2.793B 0.00 Cytokinetics (CYTK) United States $2.753B 0.00 Intra-Cellular Therapies (ITCI) United States $2.701B 0.00 Sorrento Therapeutics (SRNE) United States $2.683B 0.00 Vericel (VCEL) United States $2.526B 300.94 Atea Pharmaceuticals (AVIR) United States $2.460B 0.00 Seer (SEER) $2.457B 0.00 Celldex Therapeutics (CLDX) United States $2.447B 0.00 Instil Bio (TIL) United States $2.427B 0.00 Berkeley Lights (BLI) United States $2.386B 0.00 Protagonist Therapeutics (PTGX) United States $2.306B 0.00 Morphic Holding (MORF) United States $2.297B 0.00 Myovant Sciences (MYOV) United Kingdom $2.241B 0.00 Dynavax Technologies (DVAX) United States $2.233B 0.00 Ligand Pharmaceuticals (LGND) United States $2.206B 32.27 Alector (ALEC) United States $2.186B 0.00 Amarin (AMRN) Ireland $2.150B 544.00 Arcus Biosciences (RCUS) United States $2.083B 0.00 ADC Therapeutics SA (ADCT) Switzerland $2.010B 0.00 MorphoSys AG (MOR) Germany $1.994B 0.00 C4 Therapeutics (CCCC) United States $1.944B 0.00 Harmony Biosciences Holdings (HRMY) United States $1.932B 32.90 Castle Biosciences (CSTL) United States $1.931B 0.00 Revance Therapeutics (RVNC) United States $1.924B 0.00 Deciphera Pharmaceuticals (DCPH) United States $1.828B 0.00 Inovio Pharmaceuticals (INO) United States $1.817B 0.00 Global Blood Therapeutics (GBT) United States $1.791B 0.00 Codexis (CDXS) United States $1.747B 0.00 NGM Biopharmaceuticals (NGM) United States $1.688B 0.00 MiMedx (MDXG) United States $1.652B 0.00 Bionano Genomics (BNGO) United States $1.627B 0.00 PHARMA MAR SA (PHMMF) Spain $1.623B 0.00 Dicerna Pharmaceuticals (DRNA) United States $1.600B 0.00 OXFORD BIOMEDCL (OXBDF) United Kingdom $1.586B 0.00 Zymeworks (ZYME) Canada $1.530B 0.00 Ocugen (OCGN) United States $1.509B 0.00 Immunocore Holdings (IMCR) United Kingdom $1.490B 0.00 Avid Bioservices (CDMO) United States $1.487B 606.00 Arcturus Therapeutics Holdings (ARCT) United States $1.443B 0.00 Sangamo Therapeutics (SGMO) United States $1.440B 0.00 Agenus (AGEN) United States $1.438B 0.00 PureTech Health (PRTC) United States $1.433B 0.00 Nurix Therapeutics (NRIX) United States $1.430B 0.00 BioAtla (BCAB) United States $1.389B 0.00 REGENXBIO (RGNX) United States $1.376B 0.00 Scholar Rock Holding (SRRK) United States $1.362B 0.00 Zealand Pharma (ZEAL) Denmark $1.345B 0.00 Y-mAbs Therapeutics (YMAB) United States $1.341B 0.00 UniQure (QURE) Netherlands $1.336B 4.55 Travere Therapeutics (TVTX) United States $1.325B 0.00 Repare Therapeutics (RPTX) Canada $1.262B 0.00 Precigen (PGEN) United States $1.250B 0.00 Bluebird Bio (BLUE) United States $1.237B 0.00 BeyondSpring (BYSI) United States $1.224B 0.00 Coherus BioSciences (CHRS) United States $1.222B 0.00 MannKind (MNKD) United States $1.198B 0.00 Fulcrum Therapeutics (FULC) United States $1.197B 0.00 Genetron Holdings (GTH) China $1.181B 0.00 Northwest Biotherapeutics (NWBO) United States $1.143B 0.00 Forma Therapeutics Holdings (FMTX) United States $1.139B 0.00 Inhibrx (INBX) United States $1.081B 0.00 Nkarta (NKTX) United States $1.064B 0.00 Merus (MRUS) Netherlands $1.004B 0.00 Sutro Biopharma (STRO) United States $1.002B 0.00 Mersana Therapeutics (MRSN) United States $1.000B 0.00 Zealand Pharma (ZLDPF) Denmark $0.997B 0.00 KaloBios Pharmaceuticals (HGEN) United States $0.985B 0.00 RAPT THERAPTICS (RAPT) United States $0.964B 0.00 Kadmon Holdings (KDMN) United States $0.944B 0.00 Vanda Pharmaceuticals (VNDA) United States $0.931B 28.86 VBI Vaccines (VBIV) United States $0.924B 0.00 Bicycle Therapeutics (BCYC) United Kingdom $0.911B 0.00 IDEAYA Biosciences (IDYA) United States $0.902B 0.00 Shattuck Labs (STTK) United States $0.890B 0.00 Avidity Biosciences (RNA) United States $0.860B 0.00 Syndax Pharmaceuticals (SNDX) United States $0.851B 0.00 Prometheus Biosciences (RXDX) United States $0.848B 0.00 Mesoblast (MESO) Australia $0.847B 0.00 Immatics (IMTX) Germany $0.835B 0.00 Curis (CRIS) United States $0.811B 0.00 Adaptimmune Therapeutics (ADAP) United Kingdom $0.807B 0.00 Cara Therapeutics (CARA) United States $0.790B 98.63 Keros Therapeutics (KROS) United States $0.785B 0.00 Precision BioSciences (DTIL) United States $0.749B 0.00 Xenon Pharmaceuticals (XENE) Canada $0.726B 0.00 Pharming Group (PHAR) Netherlands $0.714B 0.00 Adagene (ADAG) China $0.703B 0.00 AnaptysBio (ANAB) United States $0.703B 0.00 Affimed (AFMD) Germany $0.692B 0.00 Lexicon Pharmaceuticals (LXRX) United States $0.682B 12.42 Bolt Biotherapeutics (BOLT) United States $0.661B 0.00 Pliant Therapeutics (PLRX) United States $0.656B 0.00 Cellectis S.A (CLLS) France $0.654B 0.00 DBV Technologies S.A (DBVT) France $0.651B 0.00 Sinovac Biotech (SVA) China $0.642B 6.47 G1 THERAPEUTICS (GTHX) United States $0.640B 0.00 Pharming Group (PHGUF) Netherlands $0.632B 25.25 Brooklyn ImmunoTherapeutics (BTX) United States $0.624B 0.00 Anika Therapeutics (ANIK) United States $0.622B 0.00 Spero Therapeutics (SPRO) United States $0.619B 0.00 Akoya Biosciences (AKYA) United States $0.593B 0.00 AC Immune SA (ACIU) Switzerland $0.591B 0.00 ALBIREO PHARMA (ALBO) United States $0.588B 0.00 Seres Therapeutics (MCRB) United States $0.588B 0.00 VistaGen Therapeutics (VTGN) United States $0.586B 0.00 ChromaDex (CDXC) United States $0.582B 0.00 Clovis Oncology (CLVS) United States $0.571B 0.00 MeiraGTx Holdings (MGTX) United States $0.554B 0.00 Epizyme (EPZM) United States $0.528B 0.00 Nabriva Therapeutics AG (NBRV) Ireland $0.527B 0.00 Vaccitech (VACC) United Kingdom $0.519B 0.00 Inventiva S.A (IVA) France $0.510B 0.00 Autolus Therapeutics (AUTL) United Kingdom $0.500B 0.00 Selecta Biosciences (SELB) United States $0.499B 0.00 Cel-Sci (CVM) United States $0.498B 0.00 Intercept Pharmaceuticals (ICPT) United States $0.495B 0.00 Basilea Pharmaceutica AG (BPMUF) Switzerland $0.494B 0.00 Clene (CLNN) United States $0.492B 0.00 XBiotech (XBIT) United States $0.485B 0.00 Oncobiologics (OTLK) United States $0.484B 0.00 Compugen (CGEN) Israel $0.480B 0.00 Verastem (VSTM) United States $0.479B 0.00 Geron (GERN) United States $0.465B 0.00 Gritstone Bio (GRTS) United States $0.455B 0.00 Cybin (CYBN) Canada $0.447B 0.00 Lineage Cell Therapeutics (LCTX) United States $0.422B 0.00 INmune Bio (INMB) United States $0.420B 0.00 Forte Biosciences (FBRX) United States $0.414B 0.00 Clearside Biomedical (CLSD) United States $0.410B 0.00 Athenex (ATNX) United States $0.399B 0.00 Amryt Pharma (AMYT) United Kingdom $0.398B 0.00 ANI Pharmaceuticals (ANIP) United States $0.387B 10.57 Codiak BioSciences (CDAK) United States $0.384B 0.00 BioDelivery Sciences (BDSI) United States $0.381B 11.70 Athersys (ATHX) United States $0.380B 0.00 Cue Biopharma (CUE) United States $0.378B 0.00 SQZ Biotechnologies (SQZ) United States $0.373B 0.00 Starpharma Holdings (SPHRY) Australia $0.365B 0.00 Prima BioMed (IMMP) Australia $0.361B 0.00 Pieris Pharmaceuticals (PIRS) United States $0.360B 0.00 Aeglea BioTherapeutics (AGLE) United States $0.356B 0.00 XOMA (XOMA) United States $0.352B 148.19 ZIOPHARM Oncology Inc (ZIOP) United States $0.351B 0.00 Orchard Therapeutics (ORTX) United Kingdom $0.346B 0.00 Neoleukin Therapeutics (NLTX) United States $0.346B 0.00 Theratechnologies (THTX) Canada $0.344B 0.00 Arbutus Biopharma (ABUS) United States $0.340B 0.00 ProQR Therapeutics (PRQR) Netherlands $0.335B 0.00 CytomX Therapeutics (CTMX) United States $0.334B 0.00 Fortress Biotech (FBIO) United States $0.332B 0.00 Cogent Biosciences (COGT) United States $0.330B 0.00 Opthea (OPT) Australia $0.330B 0.00 AquaBounty Technologies (AQB) United States $0.329B 0.00 Syros Pharmaceuticals (SYRS) United States $0.328B 0.00 Angion Biomedica (ANGN) United States $0.328B 0.00 WAVE Life Sciences (WVE) Singapore $0.321B 0.00 EYEPOINT PHARMACEUTICALS, INC (EYPT) United States $0.315B 0.00 Puma Biotechnology (PBYI) United States $0.309B 0.00 Avalo Therapeutics (AVTX) United States $0.298B 0.00 Cardiff Oncology (CRDF) United States $0.290B 0.00 Bellus Health (BLU) Canada $0.290B 0.00 Innate Pharma S.A (IPHA) France $0.288B 0.00 IBio (IBIO) United States $0.277B 0.00 Paratek Pharmaceuticals (PRTK) United States $0.271B 0.00 Checkpoint Therapeutics (CKPT) United States $0.266B 0.00 Adicet Bio (ACET) United States $0.266B 0.00 Frequency Therapeutics (FREQ) United States $0.266B 0.00 Beyond Air (XAIR) United States $0.263B 0.00 Kaleido Biosciences (KLDO) $0.261B 0.00 CorMedix Inc (CRMD) United States $0.246B 0.00 OVID THERAPEUTC (OVID) United States $0.240B 2.10 Kamada (KMDA) Israel $0.240B 19.93 Adverum Biotechnologies (ADVM) United States $0.238B 0.00 Seelos Therapeutics (SEEL) United States $0.225B 0.00 AVEO Pharmaceuticals (AVEO) United States $0.220B 0.00 OSMOTICA PHARM (OSMT) United States $0.220B 0.00 Kala Pharmaceuticals (KALA) United States $0.220B 0.00 Trevena (TRVN) United States $0.217B 0.00 NextCure (NXTC) United States $0.210B 0.00 Talis Biomedical (TLIS) United States $0.207B 0.00 TELA Bio (TELA) United States $0.190B 0.00 GENFIT S.A (GNFT) France $0.190B 0.00 SESEN BIO, INC (SESN) United States $0.186B 0.00 HOOKIPA Pharma (HOOK) United States $0.180B 0.00 ADMA Biologics Inc (ADMA) United States $0.178B 0.00 Dyadic (DYAI) United States $0.177B 0.00 Enzo Biochem (ENZ) United States $0.177B 52.29 ObsEva SA (OBSV) Switzerland $0.176B 0.00 Aptinyx (APTX) United States $0.176B 0.00 VolitionRX (VNRX) United States $0.175B 0.00 Erytech Pharma SA (ERYP) France $0.171B 0.00 Biofrontera AG (BFRA) Germany $0.169B 0.00 ANIXA BIOSCIENCES INC (ANIX) United States $0.168B 0.00 F-star Therapeutics (FSTX) United Kingdom $0.163B 0.00 POXEL SA FRANCE (PXXLF) France $0.161B 0.00 VTv Therapeutics (VTVT) United States $0.156B 0.00 PHASEBIO PHARMA (PHAS) United States $0.156B 0.00 LogicBio Therapeutics (LOGC) United States $0.153B 0.00 Strongbridge Biopharma (SBBP) United States $0.153B 0.00 Applied Genetic Technologies (AGTC) United States $0.152B 0.00 Cyclerion Therapeutics (CYCN) United States $0.148B 0.00 Galena Biopharma (SLS) United States $0.147B 0.00 Catalyst Biosciences (CBIO) United States $0.144B 0.00 Eyenovia (EYEN) United States $0.143B 0.00 Novogen (KZIA) Australia $0.141B 0.00 Synlogic (SYBX) United States $0.140B 0.00 Liquidia Technologies (LQDA) United States $0.139B 0.00 Evofem Biosciences (EVFM) United States $0.138B 0.00 Abeona Therapeutics (ABEO) United States $0.134B 0.00 Nicox SA (NICXF) France $0.134B 0.00 Orgenesis (ORGS) United States $0.131B 267.50 Eton Pharmaceuticals (ETON) United States $0.130B 0.00 Purple Biotech (PPBT) Israel $0.129B 0.00 Viridian Therapeutics (VRDN) United States $0.128B 0.00 X4 Pharmaceuticals (XFOR) United States $0.127B 0.00 Voyager Therapeutics (VYGR) United States $0.124B 7.09 Exicure (XCUR) United States $0.123B 0.00 Entera Bio (ENTX) Israel $0.116B 0.00 Cocrystal Pharma (COCP) United States $0.114B 0.00 Cidara Therapeutics (CDTX) United States $0.114B 0.00 Vascular Biogenics (VBLT) Israel $0.113B 0.00 Yumanity Therapeutics (YMTX) United States $0.111B 0.00 Palatin Technologies (PTN) United States $0.110B 0.00 Leap Therapeutics (LPTX) United States $0.103B 0.00 ASLAN Pharmaceuticals (ASLN) Singapore $0.101B 0.00 Pluristem Therapeutics (PSTI) Israel $0.096B 0.00 Aytu BioPharma (AYTU) United States $0.096B 0.00 ATyr Pharma (LIFE) United States $0.093B 0.00 Celsion (CLSN) United States $0.092B 0.00 Lumos Pharma (LUMO) United States $0.091B 0.00 ARAVIVE, INC (ARAV) United States $0.089B 0.00 Aptevo Therapeutics (APVO) United States $0.088B 0.00 AEterna Zentaris (AEZS) United States $0.087B 0.00 Aadi Biosciences (AADI) United States $0.083B 0.00 Zosano Pharma (ZSAN) United States $0.082B 0.00 DiaMedica Therapeutics (DMAC) United States $0.081B 0.00 Liminal BioSciences (LMNL) Canada $0.078B 0.00 Edesa Biotech (EDSA) Canada $0.078B 0.00 Evogene (EVGN) Israel $0.077B 0.00 Stealth BioTherapeutics (MITO) Cayman Islands $0.077B 0.00 Emmaus Life Sciences (EMMA) United States $0.076B 0.00 Vyant Bio (VYNT) United States $0.076B 0.00 Protalix BioTherapeutics (PLX) Israel $0.075B 0.00 AIkido Pharma (AIKI) United States $0.074B 0.00 Vaccinex (VCNX) United States $0.074B 0.00 TRACON Pharmaceuticals (TCON) United States $0.073B 0.00 ABVC BioPharma (ABVC) United States $0.071B 0.00 Adocia (ADOCY) France $0.069B 0.00 Advaxis (ADXS) United States $0.068B 0.00 Celyad SA (CYAD) Belgium $0.068B 0.00 Organovo Holdings (ONVO) United States $0.067B 0.00 Longeveron (LGVN) United States $0.067B 0.00 Idera Pharmaceuticals (IDRA) United States $0.058B 0.00 AnPac Bio-Medical Science (ANPC) China $0.055B 0.00 Windtree Therapeutics (WINT) United States $0.052B 0.00 Genetic Technologies (GENE) Australia $0.052B 0.00 Antibe Therapeutics (ATBPF) Canada $0.052B 0.00 Oncotelic Therapeutics (OTLC) United States $0.051B 0.00 Cyclacel Pharmaceuticals (CYCC) United States $0.050B 0.00 BioCardia (BCDA) United States $0.050B 0.00 Cyclo Therapeutics (CYTH) United States $0.050B 0.00 Cytocom (CBLI) United States $0.049B 0.00 ARIDIS PHARMACT (ARDS) United States $0.049B 0.00 Vallon Pharmaceuticals (VLON) United States $0.048B 0.00 Acorda Therapeutics (ACOR) United States $0.047B 0.98 Pulmatrix (PULM) United States $0.046B 0.00 Enveric Biosciences (ENVB) United States $0.043B 0.00 Soligenix (SNGX) United States $0.042B 0.00 Alimera Sciences (ALIM) United States $0.041B 0.00 Invo BioScience (INVO) United States $0.040B 0.00 GeoVax Labs (GOVX) United States $0.039B 0.00 PLANET GREEN HOLDINGS CORP (PLAG) China $0.037B 0.00 Happiness Biotech Group (HAPP) China $0.035B 0.00 Timber Pharmaceuticals (TMBR) United States $0.034B 0.00 Palisade Bio (PALI) United States $0.032B 0.00 Lexaria Bioscience (LEXX) Canada $0.032B 0.00 Benitec Biopharma (BNTC) United States $0.031B 0.00 Prana Biotechnology (ATHE) Australia $0.031B 0.00 ZIVO Bioscience (ZIVO) United States $0.029B 0.00 ThermoGenesis Holdings (THMO) United States $0.029B 0.00 IMMURON (IMRN) Australia $0.028B 0.00 Titan Pharmaceuticals (TTNP) United States $0.022B 0.00 Sonnet BioTherapeutics Holdings (SONN) United States $0.017B 0.00 CollPlant Biotechnologies (CLGN) Israel $0.000B 0.00 ImmunityBio (IBRX) United States $0.000B 0.00 PDL BioPharma (PDLI) United States $0.000B 0.00 UROGEN PHARMA (URGN) United States $0.000B 0.00

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